Prevalence of venous thromboembolism

• Common disorder, associated with high morbidity and mortality
• VTE occurs at an annual incidence of 1-2 in 1000 adults
• Clinical manifestations are deep vein thrombosis (DVT) and its major complication pulmonary embolism (PE)
• 2/3 of episodes manifest as DVT and 1/3 as PE with or without DVT
• Risk for VTE increase sharply after age 45
• Rates are slightly higher in men than in women
• Different incidences among ethnic groups (higher rates in Caucasians than in Asians or Hispanics)
• Major outcomes: death, recurrence, post-thrombotic syndrome and major bleeding due to anticoagulation
• Death occurs within one month of an episode in about 6% of those with DVT and 10% of those with PE

• Pregnancy
• Surgery
• Lack of exercise
• Low water consumption; dehydration cure
• Age (> 60 years)
• Varices
• Overweight
• Smoking
• Intake of contraceptives
• Hormone intake during menopause
• Heart insufficiency
• Acute infection (pulmonary infection, COVID-19 etc.)
• Chronic inflammatory diseases as rheumatism
• Tumors
• Bone fractures
• Thrombotic events in own anamnesis